A full listing of our work can be found at the two following sites (Research Gate and PubMed) and below.
ResearchGate: https://www.researchgate.net/profile/Stephanie_Watts
PubMed: https://www.ncbi.nlm.nih.gov/myncbi/stephanie.watts.1/bibliography/public/
The PubMed site is most up to date (5/2024)
1991
Watts, S. W. and Cohen, M. L.: Heterogeneous response of rat genitourinary tissues to substance P, bradykinin, bombesin, and calcitonin-gene related peptide. Peptides, 12: 1057-1062, 1991. PMID: 1724795, 1991.
1992
Watts, S. W. and Cohen, M. L.: Characterization of the contractile serotonergic receptor in guinea pig trachea with agonists and antagonists. J. Pharmacol. Exp. Ther., 260: 1101-1106, 1992. PMID: 1312158, 1992.
1993
Watts, S. W. and Cohen, M. L.: Further evidence that the guinea pig tracheal contractile serotonergic receptor is a 5-HT2 receptor: use of 5-methyltryptamine and dipropyl-5-carboxamidotryptamine, J. Pharmacol. Exp. Ther., 264: 271-275, 1993. PMID: 8423530, 1993.
Watts, S. W. and Cohen, M. L. : Time-dependent improvement of guinea pig tracheal contractility: modification by cyclooxygenase inhibitors, J. Pharmacol. Exp. Ther., 266: 950-957, 1993. PMID: 8394924, 1993.
Watts, S. W., Traub, O., Myers, J.-H., Lamb, F. S. and Webb, R. C.: Effect of ramipril on a-receptor-mediated oscillatory contractions in tail artery of hypertensive rats, Eur. J. Pharmacol., 242: 254-253, 1993. PMID: 8281989, 2003.
1994
Watts, S. W., Stengel, P. W. and S. A. Silbaugh. Serotonin receptors in respiratory smooth muscle and respiratory diseases, Drug News & Perspectives, vol. 7 (1), 19-25, 1994. Not curated on pubmed.
Watts, S. W., Baez, M., Mooney, P. Q., Johnson, B. G., Schoepp, D. D. and Cohen, M. L.: Disruption of potential alpha-helix in the G loop of the guinea pig 5-hydroxytryptamine2 (5-HT2) receptor does not prevent receptor-coupling to phosphoinositide hydrolysis, J. Neurochem., 62: 934-943, 1994. PMID: 8113814, 1994.
Watts, S. W. and Webb, R. C.: Mechanism of ergonovine-induced contraction in deoxycorticosterone acetate-salt hypertensive rats, J. Pharmacol. Exp. Ther., 269: 617-625, 1994. PMID: 8182528, 1994.
Watts, S. W., Gackenheimer, S., Gehlert, D. G. and Cohen, M. L.: Autoradiographic comparison of [125]I-LSD labelled 5-HT2A recpetor distribution in rat and guinea pig brain, Neurochem. Internat., 24: 565-574, 1994. PMID: 7981639, 1994.
Watts, S. W., Schenck, K. W. and Cohen, M. L.: Selective desensitization of the 5-HT2 receptor mediated contraction in guinea pig trachea,Can. J. Physiol. Pharmacol., 72: 463-470, 1994. PMID: 7954073, 1994.
Watts, S. W., Traub, O. and Webb, R. C.: Effects of ramipril on contractile oscillations in arteries from genetically hypertensive rats,Clin. Exp. Hypertension, 16 (6): 881-898, 1994. PMID: 7532066, 1994.
Watts, S. W., Finta, K., Lloyd, M. C., Storm, D. S. and Webb, R. C.: Enhanced vascular responsiveness to BayK 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension, Blood Pressure, 3: 340-348, 1994. PMID: 7532526, 1994.
Watts, S. W., Cox DA, Johnson BA, Schoepp DD and Cohen ML: Contractile serotonin-2A recpetor signal transduction in guinea pig trache: importantce of protein kinase C and extracellular and intracellular calcium but not phospholipase C, J. Pharmacol. Exp. Ther., 271: 832-844, 1994. PMID: 7965803, 1994.
Watts, S. W., Tsai, M.-Ling, Loch-Caruso, R. and Webb, R. C.: Gap junctional communication and vascular smooth muscle reactivity: Use of tetraethylammonium chloride,J. Vasc. Res., 31: 307-313, 1994 PMID: 79869554, 1994.
1995
Killam, A. L., Watts, S. W. and Cohen, M. L.: Role of a1 and 5-HT2 receptors in serotonin-induced contraction of rat prostate: autoradiographical and functional studies,Eur. J. Pharmacol., 273: 7-14, 1995. PMID: 773720, 1995.
Watts, S. W., Chai, S. and Webb, R. C.: Lead acetate-induced contraction in rabbit mesenteric artery: Interaction with calcium and protein kinase C, Toxicology, 99:55-65, 1995. PMID: 7762002, 1995.
Watts, S. W., Gilbert, L. and Webb, R. C.: 5-HT2B receptor mediates contraction to 5-HT in the mesenteric artery of DOCA-salt hypertensive rats, Hypertension, 26: 1056-1059, 1995. PMID: 7498967, 1995.
Tsai, M.-L., Watts, S. W., Loch-Caruso, R. and Webb, R. C.: Role of gap junctional communication in enhanced vascular reactivity in arteries from hypertensive rats, J. Hypertension, 13:1123-1133, 1995. PMID: 8586804, 1995.
1996
Cox, D. A., Watts, S. W. and Cohen, M. L.: Neomycin selectively inhibits 5-hydroxytryptamine-induced contraction in the guinea pig trachea, J. Pharmacol. Exp. Ther., 277:954-959, 1996. PMID: 8627578, 1996.
Watts, S. W., Baez, M. and Webb, R. C.: The 5-HT2B receptor and 5-HT receptor signal transduction in vascular smooth muscle from DOCA-salt hypertensive rats, J. Pharmacol. Exp. Ther., 272:1103-1113, 1996. PMID: 8627522, 1996.
Watts, S. W., Yeum, C. H., Campbell, G. and Webb, R. C.: Serotonin stimulates protein tyrosyl-phosphorylation and vascular contraction via tyrosine kinase, J. Vasc. Res., 33:288-298, 1996. PMID: 8695753, 1996.
Goud, C., Watts, S. W. and Webb, R. C.: Photorelaxation is not attenuated by inhibition of the nitric oxide cGMP pathway, J. Vasc. Res., 33: 299-307, 1996. PMID: 8695754, 1996.
Kanagy, N. L., Sarkar, R. J., Watts, S. W. and Webb, R. C.: Non-cGMP, paracrine effects of nitric oxide in the vasculature, in Endocrinology of the Vasculature, ed. by J. R. Sowers and M. Walsh, Humana Press, Totawa, pp.37-47, 1996.
Javid, P. J., Watts, S. W. and Webb, R. C.: Inhibition of nitric oxide-induced vasodilation by gap junction inhibitors: a potential role for cGMP-independent nitric oxide pathway, J. Vasc. Res., 33: 395-404, 1996. PMID: 8862145, 1996.
Watts, S. W. and Webb, R. C.: Vascular gap junctional communication is increased in mineralocorticoid-salt hypertension, Hypertension, 28:888-893, 1996.PMID: 8901840, 1996.
Watts, S. W.: Serotonin activates the mitogen-activated protein kinase pathway in vascular smooth •muscle: Use of the mitogen activated protein kinase kinase inhibitor PD098059, J. Pharmacol. Exp. Ther., 279:1541-1550, 1996. PMID: 8968381, 1996.
1997
Watts, S. W. and Webb, R. C.: Vascular gap junctional communication and heptanol-response, Hypertension, 30:306, 1997.
Tithof, P. K., Watts, S. W. and Ganey, P.: Protein tyrosine kinases are involved in the production of superoxide anion by neutrophils exposed to the mixture of polychlorinated biphenyls Aroclor 1242, Biochemical Pharmacology, 53: 1833-1842, 1997. PUBMED
Grekin, R., Dumont, C., Vollmer, A., Watts, S. W. and Webb, R. C.: Mechanisms in the pressor effect of hepatic portal venous fatty acid infusion, American Journal of Physiology, 273: R342-R330, 1997. PMID: 9249567, 1997.
Watts, S. W.: The 5-HT2B receptor antagonist LY272015 inhibits 5-HT-induced contraction in the aorta of mineralocorticoid-salt hypertensive rats, J. Serotonin Res., 4(3):197-206, 1997. Not curated by PubMed.
1998
Monroe, K. and Watts, S. W.: The vascular reactivity of melatonin, General Pharmacology, 30:931-935, 1998. PMID: 9457478, 1998.
Florian, J. A. and Watts, S. W.: Integration of MEK activation in vascular 5-HT2A receptor signal transduction, J. Pharmacol. Exp. Ther., 284:346-355, 1998. PMID: 9435197, 1998.
Watts, S. W.: The development of enhanced arterial serotonergic hyperresponsiveness in mineralocorticoid hypertension, J. Hypertension, 16:811-822, 1998. PMID: 9663921, 1998.
Watts, S. W.: Activation of the mitogen activated protein kinase pathway via the 5-HT2A receptor, Ann New York Acad. Sci., 861:162-168, 1998. PMID: 9928253, 1998.
Watts, S. W., Florian, J. A. and Monroe, K. M.: Dissociation of angiotensin II-stimulated activation of mitogen activated protein kinase kinase from vascular contraction, J. Pharmacol. Exp. Ther., 286:1431-1438, 1998. PMID: 9732408, 1998.
1999
Florian, J. A. and Watts, S. W.: Epidermal Growth Factor: a potent vasoconstrictor in experimental hypertension, Am. J. Physiol., 276:H976-H983, 1999. PMID: 10070082, 1999.
Watts, S. W. and Fink, G. D.: The 5-hydroxytryptamine2B receptor antagonist LY272015 is antihypertensive in severely hypertensive deoxycorticosterone acetate salt rats, Am. J. Physiol., 276:H944-H952, 1999. PMID: 10070078, 1999.
Watts, S. W., Florian, J. A. and Banes, A.: Mechanisms of 5-HT2A receptor activation of the mitogen activated protein kinase pathway in vascular smooth muscle, J. Pharmacol. Exp. Ther., 291:1179-1187, 1999. PMID: 10565840, 1999.
Watts, S. W. and Harris, B. J.: Is functional upregulation of the 5-HT2B receptor in deoxycorticosterone acetate salt-treated rats blood pressure-dependent?, Gen. Pharmacol, The Vasc. System, 33(6): 439-447, 1999. PMID: 10647769, 199.
2000
Watts, S. W., Fink, G. D., Silver, P. and Cushing, D.J.: Interaction of the beta receptor adrenergic antagonist bucindolol with serotonergic receptors, J. Cardiovasc. Pharmacol. 35(1):29-36, 2000. PMID: 10630730, 2000.
Watts, S. W.: 5-HT-induced potentiation of ET-1 and NE-induced Contraction is MAPK pathway-dependent, Hypertension, 35:244-248, 2000. PMID: 10642305, 2000.
Russell, A. and Watts, S. W.: Vascular reactivity of the isolated thoracic aorta of the C57BL/6J mouse. J. Pharmacol. Exp. Ther., 294:598-604, 2000. PUBMED?
Melis, A., Watts, S. W., Florian, J., Klarr, S. and Webb, R. C.: Insulin-like growth factor inhibits vascular contraction to serotonin: involvement of tyrosine phosphatase, Gen. Pharmacol., The Vasc. System, 34:137-145, 2000. PMID: 10974421, 2000.
2001
Ballew, JR, Watts, S.W. and Fink, G.D.: Effects of salt intake and angiotensin II on vascular reactivity to endothelin-1, J. Pharmacol. Exp. Ther., 296:345-350, 2001. PMID: 1160616, 2001.
McKune, C. and Watts, S. W.: Characterization of the serotonin receptor mediating contraction in the mouse thoracic aorta, J. Pharmacol. Exp. Ther.,297: 88-95, 2001. PMID: 11259531, 2001.
Xu, H., Fink, G. D., Chen, A., Watts, S. W. and Galligan, J. J.: Nitric oxide-independent effects of tempol on sympathetic nerve activity and blood pressure in normotensive rats, Am. J. Physiol. 281:H975-H980, 2001. PMID?
Atkins, K. B., Johns, D., Watts, S.W., Webb, R. C. and Brosius FC III. Decreased vascular glucose transporter expression and glucose uptake in DOCA-salt hypertension. J. Hypertens. 19:1581-1587, 2001.PMID?
Florian, J. A., Dorrance, A., Webb, R. C. and Watts, S. W.: Mineralocorticoids upregulate arterial contraction to epidermal growth factor, Am. J. Physiol. Reg Int & Comp. 281:R878-R886, 2001. PMID: 11507004, 2001.
Banes, A. K. and Watts, S. W.: Enhanced contraction to 5-HT is not due to unmasking of the 5-HT1B receptors in the mesenteric artery of the DOCA-salt rat, Hypertension, 38:891-895, 2001. PMID: 11641304, 2001.
Banes, A. K. L., Loberg, R. D., Brosius, F. C. and Watts, S. W.: Inability of serotonin to activate the c-Jun-N-terminal kinase and p38 kinase pathways in rat aortic vascular smooth muscle cells, BMC Pharmacology 2001, 1:8. PMID: 11667949, 2001.
Watts, S. W., Yang, P., Banes, A. K. and Baez, M.: Activation of Erk MAPK proteins by vascular serotonin receptors, J. Cardiovasc. Pharmacol., 38:539-551, 2001. PMID: 11588524, 2001.
Northcott, C., Florian, J. A., Dorrance, A. and Watts, S. W.: Arterial epidermal growth factor receptor expression in DOCA-salt hypertension, Hypertension, 38:1337-13341, 2001. PMID: 11751714, 2001.
2002
Banes, A. B. and Watts, S. W.: Upregulation of arterial serotonin1B and 2B receptors in DOCA-salt hypertension, Hypertension, 39:394-398, 2002. PMID: 11882579, 2002.
Watts, S. W.: Serotonin-induced contraction in mesenteric resistance arteries: signalling and changes in hypertension, Hypertension, 39:825-829, 2002. PMID: 11897772, 2002.
Johnson, R. J, Fink, G. D., Watts, S. W. and Galligan, J.J.: Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt hypertensive rats, J. Hypertension, 20(4): 665-676, 2002. PMID: 11910302, 2002.
Watts, S. W., Fink, G. D., Northcott, C. A. and Galligan, J. J.: Endothelin-1-induced venous contraction is maintained in DOCA-salt hypertension; studies with receptor agonists, Br. J. Pharmacol. 137:69-79, 2002. PMID: 12183332, 2002.
Northcott, C. A., Poy, M. N., Najjar, S. M. and Watts, S. W.: PI3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of DOCA-salt hypertensive rats, Circ. Res, 91:360-369, 2002; Editorial on page 273-275. PMID: 12193470, 2002.
Russell, A., Banes, A., Berlin, H., Fink, G.D. and Watts, S. W.: 5-Hydroxytryptamine2B receptor function is enhanced in the Nw-nitro-L-arginine hypertensive rat, J. Pharmacol. Exp. Ther., 303:179-187, 2002. PMID: 12235249, 2002.
2003
Li, L., Fink, G. D., Watts, S. W., Northcott, C. A., Galligan, J. J., Pagano, P. J. and Chen, A. F.: ET-1 increases vascular superoxide via ETA-NADPH oxidase pathway in low renin hypertension, Circulation, 107:1053-1058, 2003. PMID: 12600921, 2003.
Loberg, R., Northcott, C., Watts, S. W. and Brosius, F.: PI-3-Kinase –induced hyperreactivity in DOCA-salt hypertension is independent of GSK-3 activity, Hypertension, 41:898-902, 2003. PMID: 12629035, 2003.
Li, L., Watts, S. W., Banes, A. K., Galligan, J. J., Fink, G. D. and Chen, A. F.: NADPH oxidase derived superoxide augments endothelin-1-induced venocontriction in minealocorticoid hypertension, Hypertension, 42:316-321 2003. PMID: 12885792, 2003.
Banes, A. K.L. and Watts, S. W.: Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension, BMC Pharmacology,3:12 2003. PMID: 12974983, 2003.
2004
Northcott, C. A. and Watts, S. W.: Low Mg2+ enhances arterial spontaneous tone via PI3K in DOCA-salt Hypertension, Hypertension, 43:125-130, 2004. PMID: 14638620, 2004.
Thakali, K., Fink, G. D. and Watts, S. W.: Arteries and veins desensitize differently to endothelin-1, J. Cardiovasc. Pharmacol., 43:387-393, 2004. PMID: 15076222, 2004.
Watts, S. W. and Thompson, J. M.: Characterization of the contractile 5-hydroxytryptamine receptor in the renal artery of the normotensive rat, J. Pharmacol. Exp. Ther., 309: 165-172, 2004. PMID: 14724222, 2004.
Northcott, C. A., Hayflick, J. S. and Watts, S. W.: PI3-Kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: is p110delta the culprit, Hypertension, 43:885-890, 2004. PMID: 14993194, 2004.
Northcott, C. A. and Watts, S. W.: Letter to the Editor, Response to Magnesium in Hypertension. Hypertension, 43:e29, 2004.
Ni, W., Li, M., Thakali, K., Fink, G. D. and Watts, S. W.: The fenfluramine metabolite (+)-norfenfluramine is vasoactive, J. Pharmacol. Exp. Ther., 309:845-852, 2004. PMID: 14752059, 2004.
Dai, X., Galligan, J. J., Watts, S. W., Fink, G. D. and Kreulen, D. L.: Increased O2- production and upregulation of ETB receptors by sympathetic neurons in DOCA-salt hypertensive rats, Hypertension, 43:1048-1054, 2004. PMID: 15051669, 2004.
Wehrwein, E. A., Northcott, C. A., Lobert, R. D. and Watts, S. W.: Rho/Rho kinase and PI3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension, J. Pharmacol. Exp. Ther., 309:1036 -1042, 2004. PMID: 14982964, 2004.
Slovut, D. P., Mehta, S., Dorrance, A. M., Brosius, F. C, Watts, S. W. and Webb, R. C.: Increased vascular sensitivity and connextin43 expression after sympathetic denervation , Cardiovasc Research, 62: 388-396, 2004. PMID: 15094358, 2004.
Ni, W., Thompson, J., Northcott, C., Lookingland, K. and Watts, S. W.: The serotonin transporter is present and functional in peripheral arterial smooth muscle, J. Cardiovasc. Pharmacol., 43:770-781, 2004. PMID: 15167270, 2004.
Watts, S. W.: C3 or not C3: that is the question. Hypertension, 44:25-26, 2004. PMID: 15123574, 2004.
2005
Wang, H., Galligan, J. J., Chen, A. L., Watts, S. W. and Fink, G. D.: Endothelin in the splanchnic vascular bed of DOCA-salt hypertensive rats, Am. J. Physiol Heart Circ, 288:H72-H736, 2005. PMID: 15471983, 2005.
Atkins, K. B., Northcott, C. A., Watts, S. W. and Brosius, F. C.: Effect of PPARg ligands on vascular smooth muscle marker expression in hypertensive and normal arteries, Am J Physiol. Heart Circ, 288:H235-H243, 2005. PMID: 15345487, 2005.
Toews, M.L., Watts, S. W. and Beckman, B. S.: Preserving and promoting our discipline: pharmacology students speak out. Mol. Interven. 5:4-7, 2005. PMID: 15731498, 2005.
Watts, S. W.: 5-HT in Systemic Hypertension: friend, foe or fantasy? Clinical Sci., 108:399-412, 2005. PMID: 15831089, 2005.
Thakali, K., Demel, S. L., Fink, G. D. and Watts, S. W.: Endothelin-1 (ET-1)-induced contraction in veins is independent of hydrogen peroxide (H2O2), Am. J. Physiology Heart Circ, 289:H1115-1122, 2005. PMID: 15908460, 2005.
Ni, W., Wilhelm, C. S., Bader, M., Murphy, D. L., Lookingland, K. and Stephanie W. Watts: (+)-Norfenfluramine-induced arterial contraction is not dependent on endogenous 5-HT or 5-HTT, J. Pharmacol. Exp. Ther., 314L953-960, 2005. PMID: 15901794, 2005.
Northcott, C. A. and Watts, S. W.: Upregulated function of phosphoinositide-3-kinase (PI-3-K) in genetically hypertensive rats: a moderator of arterial hypercontractility, Clin. Exper. Physiol. Pharmacol., 32:851-858, 2005. PMID: 16173947, 2005.
Xu, H., Bian, X., Watts, S. W., and Hlavacova, A.: Activation of vascular BK channel by tempol in DOCA-salt hypertensive rats, Hypertension, 46:1154-1162, 2005. PMID: 16216988, 2005.
Watts, S. W.: Vasoconstriction caused by the ATP synthase subunit coupling factor 6: a new function for an historical enzyme, Hypertension, 46:1100-1102, 2005. PMID: 16230522, 2005.
2006
Thakali, K., Davenport, L., Fink, G. D. and Watts, S. W.: Pleiotropic effects of hydrogen peroxide in arteries and veins from normotensive and deoxycorticosterone acetate-salt hypertensive rats, Hypertension, 47:482-487, 2006. PMID: 16432037.
Ni, W. and Watts, S. W.: 5-HT in the cardiovascular system: focus on the serotonin transporter (SERT), Clin. Exp. Pharmacol. Physiol, 33:575-583, 2006. PMID: 16789923, 2006.
Thakali K. M., Lau, Y., Fink, G. D., Galligan, J. J., Chen, A. F. and Watts, S. W.: Mechanisms of hypertension induced by nitric oxide (NO) deficiency: focus on venous function, J. Cardiovasc Pharmacol., 47:742-740, 2006. PMID: 16810074, 2006.
Ni, W., Lookingland, K. and Watts, S. W.: Arterial 5-HT transporter function is impaired in DOCA-salt hypertensive but not spontaneously hypertensive rats, Hypertension, 48:134-140, 2006. PMID: 16754787, 2006.
Ogden, K., Thompson, J. M., Hickner, Z., Huang, T., Tang D. D. and Watts, S. W.: A new signaling paradigm for serotonin: Use of Crk-Associated substrate in arterial contraction, Am. J. Physiology Heart Circ Phys, 291:H2857-H2863, 2006. PMID; 16861698, 2006.
Ni, W.,Lookingland, L. and Watts, S. W.: Response to “Blood pressure in mutant rats lacking the 5-hydroxytryptamine (5-HT) transporter, Hypertension, ePrint, Oct 2006.
2007
Szasz, T., Thakali, K., Fink, G. D. and Watts, S. W.: A comparison of arteries and veins in oxidative stress: producers, destroyers, function and disease, Soc. Exp. Biol. Med, 232:27-37, 2007. PMID: 17202583, 2007.
Thakali, K., Davenport, L., Fink, G. D. and Watts, S. W.: Cyclooxygenase, p38 MAPK, Erk MAPK, Rho Kinase and Src mediate hydrogen peroxide induced contraction of rat thoracic aorta and vena cava, J. Pharmacol. Exp. Ther., 320:236-243, 2007. PMID: 17003231.
Rondelli, C. , Kayal, A., Szasz, T., Thakali, K., Watson, R. E., Rovner, A. S., Eddinger, T. J., Fink G. D. and Watts, S. W. Preferential myosin heavy chain isoform B expression may contribute to the faster velocity of contraction in veins vs arteries. J Vasc Res, 44:264-272, 2007. PMID: 17377397, 2007.
Watts, S. W., Rondelli, C., Thakali, K., Pervaiz, M., Watson, R. and Fink, G. D.: Morphologic and Biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats, Am. J. Physiology Heart Circ, 292:H2438-2448, 2007. PMID: 17237246.
Ni, W, Fink, G. D. and Watts, S. W.: The 5-HT2A receptor is involved in (+) norfenfluramine-induced arterial conraction and blood pressure increase in DOCA-salt hypertension, J. Pharmacol. Exp. Ther. 321:485-491, 2007. PMID: 17289838, 2008.
Fink, G. D., Li, M., Lau, Y., Osborne, J. and Watts, S. W.: Chronic activation of endothelin ETB receptors: A new model of experimental hypertension, Hypertension, 50:512-518, 2007.
Linder, A. E., Ni, W., Diaz, J. L., Szasz, T., Burnett, R. and Watts, S. W.: 5-HT in veins: not all in vain, invited Perspectives in Pharmacology J. Pharmacol. Exp. Ther., 323:415-421, 2007. PMID: 17671100, 2007.
Linder, A.E., Thakali, K., Thompson, J., Watts, S. W., Webb, R. C. and Leite, R.: Methyl-b-cyclodextrin prevents angiotensin II-induced tachyphylactic contractile responses in rat aorta, J Pharmacol Exp Ther., 323:78-84, 2007. PMID: 17636007.
Ogden, K. K., Falck, J. R. and Watts, S. W.: The cytochrome P450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta, J. Pharmacol. Exp. Ther., 323:606-613, 2007. PMID: 17687070, 2008.
Watts, S. W., Thakali, K., Rondelli, C and Fink, G. D.: Big ET-1 into vasoactive peptides in arteries and veins, Vascular Pharmacology, 47:302-312, 2007. PMID: 17904426, 1007.
2008
Huang J, Lin SC, Nadershahi A, Watts SW, Sarkar R. Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite., J Vasc Surg. 47(3):599-607, 2008. PMID: 18295111, 2008.
Linder, A. E., Diaz, J., Ni, W., Szasz, T., Burnett, R. and Watts, S. W.: Vascular reactivity, 5-HT uptake and blood pressure in the serotonin transporter knockout rat, Am J Physiol Heart Circ Physiol, 294:H1745-H1752, 2008. PMID: 18263707, 20018.
Thakali, K., Galligan, J. J., Fink, G. D., Gariepy, C. E. and Watts, S. W.: Pharmacological endothelin receptor interaction occurs in veins but not arteries, Vascular Pharmacology, 49:6-13, 2008. PMID: 18485831, 2008.
Ni, W, Geddes, T. J., Priestley, J. R. C., Szasz, T., Kuhn, D. M. and Watts, S. W.: The existence of a local serotonergic system in peripheral arteries, Br J Pharmacol, 154:663-674, 2008. PMID: 18414394, 2008.
Diaz, J., Ni, W., King, A., Fink, G. D. and Watts, S. W.: 5-hydroxytryptamine lowers blood pressure in normotensive and hypertensive rats. J Pharmacol Exp Ther, 325:1031-1038, 2008. PMID: 18305011, 2008.
Linder, A. E., Ni, W., Szasz, T., Burnett, R., Diaz, J., Geddes, T. J., Kuhn, D. M. and Watts, S.W.: A serotonergic system in veins: serotonin-transporter independent uptake, J. Pharmacol. Exp. Ther., 325:714-722, 2008. PMID: 18322152, 2008.
Ni, W., Zhou, H., Diaz, J., Murphy, D. L., Haywood, J. R. and Watts, S. W.: Lack of the serotonin transporter does not prevent mineralocorticoid hypertension in rat and mouse, Eur. J Pharmacol, 589:225-227, 2008. PMID: 18573249, 2008.
Szasz, T., Thompson, J. M. and Watts, S. W.: A comparison of reactive oxygen species metabolism in aorta and vena cava of the normal rat: focus on xanthine oxidase, Am J Physiol Heart Circ Physiol 295:H1341-H1350, 2008. PMID: 18660442, 2008.
Watts, S. W.: The beginning of a fantastic, unanswered question: is 5-HT involved in systemic hypertension, Am J Physiol Heart Circ Physiology, 295:H915-H916, 2008. PMID: 18775854, 2008.
Li, M., Dai, X., Watts, S.W., Kreulen, D. and Fink, G. D.: Increased superoxide levels in ganglia and sympathoexcitation are involved in S6c-induced hypertension. Am J Physiol Reg Integr Comp Physiol, 295:R1546-R1554, 2008.
2009
Watts, S. W.: The love of a lifetime: 5-HT in the cardiovascular system, Am J Physiol Reg Integr Comp Physiol, 296:R252-R256, 2009. PMID 18753260
Szasz, T., Eddy, S., Paulauskis, J., Burnett, R., Ellekilde, M., Iovanna, J. L. and Watts, S. W.: Differential expression of pancreatitis associated protein and thrombospondins in arterial versus venous tissues, J Vasc Res, 46:551-560, 2009. PMID: 19571575, 2009.
Linder, A. E., Beggs, K., Burnett, R. and Watts, S. W.: Body distribution of infused serotonin in rats, Clin. Exp Pharmacol. Physiol, 36:599-601, 2009. PMID: 19207716, 2009.
Tykocki, N.R., Gariepy. C.E. and Watts, S. W.: ETB receptors in arteries and veins: multiple actions in veins, J. Pharmacol. Exp. Ther., 329:875-881, 2009. PMID: 19297422, 2009.
Watts, S. W., Priestley J.R. C. and Thompson, J. M.: Serotonylation of vascular protein important to contraction, PLoS One, May 25, e5682, 2009. PMID: 19479059, 2009.
2010
Watts SW: Endothelin receptors: what do we know and what do we need to know? Am J Physiol Regul Integr Comp Physiol, 298:R254-R260, 2010. PMID: 19907001, 2010.
Seymour E. M., Watts, S. W.: Whole grape intake impacts cardiac PPAR and NFkB activity, fibrosis and cytokine expression in rats with diastolic heart failure, Hypertension, 55:1179-1185, 2010. PMID: 20231522, 2010.
Szasz, T. and Watts, S. W.: Uric acid does not impact endothelial function of aorta from normotensive and DOCA-salt hypertensive rats, J. Pharmacol. Exp. Ther., 333: 758-763, 2010. PMID: 20215410, 2010.
Linder, A. E., Gaskell, G. L., Szasz, T., Thompson, J. M. and Watts, S. W.: Serotonin receptors in the rat jugular vein: presence and involvement in contraction, J. Pharmacol. Exp. Ther., 334:116-123, 2010. PMID: 20378714, 2010.
Tykocki, N. and Watts, S. W.: The interdependence of endothelin-1 and calcium: a review, Clin Sci, 119:361-372, 2010. PMID: 20662769.
Szasz, T, Linder AE, Davis RP, Burnett, R., Fink, G. D. and Watts, S. W.: Allopurinol does not decrease blood pressure or prevent the development of hypertension in the DOCA-salt model, J Pharmacol. Exp. Ther, 56:627-634, 2010. PMID: 20881613, 2010.
Johnson, K. B., Thompson, J. M., and Watts, S. W.: Modification of proteins by norepinephrine is important for vascular contraction, Frontiers in Vascular Physiology, Front. Physio. 1:131. doi: 10.3389/fphys.2010.00131 2010. PMID: 21423373, 2010.
Northcott, C., Watts, S. W., Chen, Y., Morris, M., Chen, A. F., and Haywood, J. R.: Small hairpin RNA adenoviral inhibition of AT1A receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat. Am J Physiol Regul Integr Comp Physiol. Nov;299(5):R1202-1211, 2010. PMID?
2011
Invited Review: Watts SW and Davis P: 5-Hydroxtryptamine Receptors in Systemic Hypertension: an arterial focus, Cardiovascular Therapeutics, 29:54-67, 2011. PMID: 20433685, 2011.
Ren W, Watts, S. W., Fanburg, B. L.: The serotonin transporter interacts with the PDGF (beta) receptor in PDGF-BB induced signaling and mitogenesis in pulmonary artery smooth muscle cells. Am J Physiol. Lung Cell Mol Physiol, 300:L486-497, 2011. PMID: 21186266, 2011.
Davis, R., Linder A. E. and Watts, S W: Lack of the serotonin transporter (SERT) reduces the ability of 5-hydroxytryptamine to lower blood pressure, Naunyn Schmied. Arch. Pharmacol, 383:543-546, 2011. PMID: 21448568, 2011.
Linder, A, Davis, R., Burnett, R. and Watts, S. W.: Comparison of the function of the serotonin transporter in the vasculature in male and female rats, Clin. Exper. Pharmacol. Physiol., 38:314-322, 2011. PMID: 21371073, 2011.
Harrison, B., Watts, S.W., Barrett, J. E., Coupet, J., Mazandarani, H., Nawoschik, S., Pangalos, M. N., Ramamoorthy, S., Schechter, L., Smith, D. L., Stack, G., Zhang, J., Zhange, G., Rosenzweig-Lipson, S. and Dunlop, J.: Characterization of Vabicaserin (SCA-136), a functionally selective 5-HT2C receptor agonist, J. Pharmacol. Exp. Ther., 337:673-680, 2011. PMID: 21402690, 2011.
Bush, C. J., Szasz, T., Johnson, K. B., Tykocki, N. R., Surewicz, W. K., Watson, R. E. and Watts, S. W.: Prion protein is expressed in the vascular system, but recombinant human PrP does not protect vascular smooth muscle cells from oxidative stress, Reinvention 4(2), October 2011. Not curated on Pubmed.
Watts, S. W., Shaw, S., Burnett, R. and Dorrance, A. M.: Indoleamine 2,3-diooxygenase in perioaortic at: mechanisms of inhibition of contraction, Am. J. Physiol. Heart Circ. Physiol, 301:H1236-1247, 2011. PMID: 21841011, 2011.
Tan T, Watts, SW and Davis RP: Drug delivery: enabling technology for drug discovery and development. IPRECIO micro infusion pump: programmable, refillable, and implantable. Front Pharmacol 2:44, Jul 29 2011. PMID: 21863140, 2011.
2012
Invited Review: Watts, S. W., Morrison S. M and Barman SM: Serotonin and Blood Pressure Regulation, Pharmacol. Rev., 64:359-388, 2012. PMID: 22407614, 2012.
Johnson K, Peterson-Jones H, Thompson, J. M., Hitomi, K., Itoh, M., Bakker ENTP, Johnson G. V. W., Colak G. and Watts, S. W.: Vena cava and aortic smooth muscle cells expression TG1 and TG4 in addition to TG2, Am. J. Physiol. Heart. Circ. Physiol., 302;H1355-1366, 2012. PMID: 22307675, 2012.
Darios E, Seitz B and Watts, S. W.: Smooth muscle pharmacology in the isolated virgin and pregnant rat uterus and cervix, J. Pharmacol. Exp. Ther., 341:587-596, 2012. PMID: 22366660, 2012.
Davis RP, Pattison J, Thompson JM, Tiniakov R, Scrogin KE and Watts, SW: 5-hydroxtryptamine (5-HT) reduces total peripheral resistance during chornic infusion: direct arterial mesenteric reslaxation is not involved, BMC Pharmacology, May 6 12(1): 4, 2012. PMID: 22559843, 2012.
Tykocki N, Jackson WF and Watts, S. W.: Reverse mode Na+/Ca2+ exchange is an important mediator of venous contraction, Pharmacol Res. 66:544-554, 2012. PMID: 22974823, 2012.
2013
Tykocki NR, Thompson JM, Jackson WF and Watts SW: Ryanodine receptors are uncoupled from contraction in rat vena cava. Cell Calcium, 53:112-119, 2013. PMID; 23177664, 2013.
Davis RP, Szasz T, Garver H, Burnett R, Tykocki N and Watts, SW: One month serotonin infusion results in a prolonged fall in blood pressure in the male deoxycorticosterone acetate (DOCA) salt rat, ACS Chem Neurosci, 4:141-148, 2013. PMID: 23336053, 2013.
Szasz T, Davis RP, Garver HS, Burnett RJ, Fink GD and Watts SW: Long term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA) salt hypertensive rats, PloS ONE, 8(2):e56046. doi:10.1371/journal.pone.0056046, 2013. PMID: 23393607, 2013.
Watts SW, Dorrance AM, Penfold ME, Rourke JL, Sinal CJ, Seitz B, Sullivan TJ, Charvat TT, Thompson JM, Burnett R and Fink GD: Chemerin connects fat to arterial contraction. Art. Thromb. Vasc. Biol, 33:1320-1328, 2013. PMID: 23559624, 2013.
2014
Seitz, B. M. and Watts, S. W.: Serotonin-induced hypotension is mediated by a decrease in intestinal resistance, Pharmacologica, 5(2): 50-54. 2014. Not curated on PubMed.
Ayala-Lopez, N, Martini M, Jackson W F, Darios E, Burnett R, Mahon B, Fink, G. D. and Watts, S. W.: Perivascular adipose tissue contains functional catecholamines. Pharmacology Research and Perspectives, Volume 2, Issue 3, June 2014. PMID: 24904751, 2014. PMID: 24904751, 2014.
Young, L., W., Thompson, J. M., Hitomi, K. and Watts, S. W.: Present and active: transglutaminases in the virgin rat uterus and cervix, The Open Access Reproductive Sciences Journal, Vol 6, 2014. [DOI: 10.2174/1874255620140708001]
Watts, S. W.: Serotonin and the sensory nerves: Meeting in the cardiovascular system, Vasc Pharmacol, 63:1-3, 2014. PMID: 25181552, 2014.
Ni, W, Watts, S. W., Ng, M, Chen, S, Glenn, D. J. and Gardner, D. G: Elimination of vitamin D receptor in vascular endothelial cells alters vascular function, Hypertension, 64:12901298, 2014. PMID: 25201890, 2014.
Penumatsa K, Abualkhair S, Wei L, Warburton R, Preston I, Hill NS, Watts S.W., Fanburg BL and Toksoz D: Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells, Cellular Signalling, 26(12):2818-2825, 2014.
2015
Ferland D, Darios ES, and Watts, S. W.: The persistence of active smooth muscle in the female rat cervix through pregnancy, Am J Obstet Gynecol, 212:244e1-8, 2014. PMID: 25108144, 2015.
Tykocki, N., Wu, B., Jackson, W. and Watts, S. W.: Divergent signalling mechanisms for venous versus arterial contraction as revealed by endothelin-1, J Vasc Surgery, 62:721-733. pii: S0741-5214(14)00358-9. doi: 10.1016/j.jvs.2014.03.010. [Epub ahead of print] 2014. PMID: 24726828, 2015.
Watts, S. W., Darios, E., Seitz, B. M., Burnett, R and Thompson, J. M.: 5-HT is a potent relaxant in rat superior mesenteric arteries? Pharmacology Research and Perspectives, e00103.doi:10.1102/prp2.103, 2015. PMID: 25692021, 2015.
Petersen-Jones, H., Johnson, K., Hitomi, K., Tykocki, N., Thompson, J. and Watts, S. W.: Transglutaminase activity is decreased in large arteries from hypertensive rats compared to normotensive controls, Am J Physiol Heart Circ Physiol, 308:H592-602, 2015. PMID: 25599570, 2015.
Watts, S. W., Tykocki, N. and Jesperson, B : Measurement of smooth muscle function in the isolated tissue bath- Applications to pharmacology research, JoVE, Jan 19; (95) doi:10.3791/52324, 2015. http://www.jove.com/video/52324. PMID: 2560585, 2015.
Darios, E.S., Barman, S. M., Orer, H. S., Morrison, S. F., Davis, R. P, Seitz, B. M., Burnett, R. and Watts, S. W.: 5-hydroxytryptamine does not reduce sympathetic nerve activity of neuroeffector function in the splanchnic circulation, Eur. J Pharmacol, 754:140-147, 2015. PMID: 25732865, 2015.
Watts, SW: The two faces of serotonin. International Innovations. http://digimag.internationalinnovation.com/launch.aspx?eid=6092cfa6-5a48-4f36-b47c-d73ca34bdbec, 2015. Not curated on pubmed.
Watts, S. W.: Trash talk by fat: chemerin as an ROS Provocateur in the vasculature, Hypertension, 115.05738, 2015.PMID: 26150433, 2015.
Ferland D.J. and Watts, S. W.: Chemerin: A comprehensive review elucidating the need for cardiovascular research. Pharmacol. Res. 99:351-361, 2015. PMID: 26211950, 2015.
Young LW, Darios ES and Watts, SW: An immunohistochemical analysis of SERT in the blood brain barrier of the male rat brain. Histochem. Cell Biol, 44:321-329, 2015. PMID: 26223876, 2015.
Ayala-Lopez, N., Jackson, W. F., Burnett, R., Wilson, J. N. and Watts, S. W.: Organic cation transporter-3 contributes to norepinephrine uptake in perivascular adipose tissue, Am J Physiol Heart Circ Physiol, 309:H1904-1914, 2015. PMID: 26432838, 2015.
Cho K, Clementi E, Levi-Schaffer F, Smalley KS, Radice S and Watts, S. W.: Pharmacological research and precision cancer medicine: A call for manuscripts. Pharmacol Res. 102: 308-309, 2015. PMID: 26542638, 2015.
Cho K, Clementi E, Levi-Schaffer F, Smalley KS, Radice S and Watts SW: Introducing a checklist for manuscript submission to Pharmacological Research. Pharmacol Res 102:319-321, 2015. PMID: 26523875, 2015.
2016
Seitz, B. M., Krieger-Burke Teresa, Fink, G. D. and Watts, S. W.: Serial measurements of splanchnic vein diameters in rats using high frequency ultrasound, Front. Pharmacol., 03 May 2016 | http://dx.doi.org/10.3389/fphar.2016.00116 PMID: 27199758, 2016.
Moore, A., Zabel, B. A., Burnett, R. and Watts, S. W.: Chemerin C9 peptide releseas catecholamines from rat adrenal medulla, Pharmacologia 7:290-295, 2016. Not curated on PubMed.
Darios, E. S., Winner, B. M., Charvat, T., Karsinksi, A., Punna, S. and Watts, S.W.: The adipokine chemerin amplifies electrical field stimulated contraction in the isolated superior mesenteric artery, Am J Physiol Heart Circ Physiol, 311:H498-H507, 2016. PMID: 27371688, 2016.
Contreras, G. A., Thelen, K., Ayala-Lopez, N. and Watts, S. W.: The distribution and adipogenic potential of perivascular adipose tissue adipocyte progenitors is dependent on sexual dimorphism and vessel location, Physiol Reports, oct;4(19). Pii: e12993, 2016. PMID: 27738018, 2016.
Watts, S. W.: Oh the places you’ll go! My many colored serotonin (apologies to Dr. Seuss), Am J Physiol Heart Circ Physiol, H1225-H1233, 2016. PMID: 27663771, 2016.
.
2017
Ayala-Lopez, N. and Watts, S. W.: New actions of an old friend: adrenergic mechanisms within perivascular adipose tissue, Br. J. Pharmacol, 174:3454-3465. doi: 10.1111/bph.13663. PMID: 27813085, 2017.
Thelen K, Ayala-Lopez N, Watts SW, Contreras GA: Expansion and adipogenesis induction of adipocyte progenitors from perivacular adipose tissue isolated by magnetic activated cell sorting, J Vis Exp 30:doi: 10.3791/55818, 2017. PMIS: 28715395, 2017.
Ferland D, Darios, E. S., Neubig, R. R., Sjogren, B., Truong, N., Torres, R., Dexheimer, T. S., Thompson J. M. and Watts, S. W.: Chemerin-induced arterial contraction is Gi and calcium-dependent, Vasc Pharmacology, 88:30-41, 2017. PMID: 28035008, 2017.
Ismail, A., Ayala-Lopez, N., Ahmad, M. and Watts, S. W.: 3T3-L1 cells and perivascular adipocytes are not equivalent in amine transporter expression, FEBS Letters 591:137-144, 2017. PMID: 27926779, 2017.
Ayala-Lopez, N., Thompson, J. M. and Watts, S. W.: Perivascular adipose tissue’s amine oxidase: impact on NE-induced contraction of mesenteric resistance arteries, Front in Physiol, Vasc Physiol, 8:37. Doi: 10.3389/fphys.2017.00037, 2017. PMID: 28228728, 2017.
Rorabaugh BR, Chakravarti B, Mabe NW, Seeley SL, Bui AD, Yang J, Watts SW, Neubig RR, Fisher RA. Regulator of G protein signaling 6 protects the heart from ischemic injury. J Pharmacol Exp Ther. 2017 Mar;360(3):409-416. doi: 10.1124/jpet.116.238345. Epub 2016 Dec 29.PMID: 28035008, 2017.
Seitz BM, Orer H, Krieger-Burke T, Darios ES, Thompson JM, Fink GD, Watts SW. 5-HT causes splanchnic venodilation. Am J Physiol Heart Circ Physiol. 2017 Jun 16:ajpheart.00165.2017. doi: 10.1152/ajpheart.00165.2017. [Epub ahead of print] PMID: 28626072, 2017.
Thelen, K. Ayala-Lopez, N. Watts, S. W. and Conteras G: The isolation, expansion and induction of adipocyte progenitors from perivascular adipose tissue, invited methods article, J Vis Exp Jun 30 (124): 55818. doi: 10.3791/55818. PMDI: 28715395, 2017.
2018
Grobbel, M. R., Shavik, S. M., Darios, E., Watts, S. W., Chuan, L. L and Roccabianca, S.: Contribution of left ventricular residual stress by myocytes and collagen: existence of inter-constituent mechanical interaction. Biomech Model Mechanobiol, doi: 10.1007/s10237-018-1007-x, 2018. PMID: 29478195, 2018.
Restini, C. B. A., Ismail A, Kumar AK, Burnett R, Garver H, Fink, G. D. and Watts, S. W.: Renal perivascular adipose tissue: form and function, Vascul Pharmacol., pii: S1537-1891(17)30297-5. doi: 10.1016/j.vph.2018.02.004, 2018. PMID: 29454047, 2018.
Ferland, S., Seitz, B. M., Darios, E., Thompson, J., Yeh, S., Mullick, A. and Watts, S. W.: Whole body but not hepatic knockdown of chemerin by antisense oligonucleotide decrases blood pressure in rats, J. Pharmacol Exp Ther., pii: jpet.117.245456. doi: 10.1124/jpet.117.245456, 2018. PMID: 29467310, 2018.
Martinez-Quinones, P. A., McCarthy, C. G., Watts, S. W., Klee, N., Komic, A., Priviero, F., Calmasini, F., Warner, A., Chenghao, Y. and Wenceslau, C.F.: The different cells in the vessel wall and their morphological and physiological changes in hypertension, Am J Hypertension, doi:10.1093/ajh/hpy083, 2018. PMID: 29788246, 2018.
Watts, S. W., Darios, E. M., Mullick, A. E., Garver, H., Saunders T. L., Hughes, E. D., Filipiak, W. E., Zeidler, M. G., McMullen, N., Sinal, C. J., Kumar, R. K., Ferland, D. J. and Fink, G. D.: The chemerin knockout rat reveals chemerin dependence in female but not male experimental hypertension, FASEB J, doi:10/1096/fj.201800479, 2018. PMID: 29906243, 2018.
Thelen, K., Watts, S. W. and Contreras G. A.: Adipogenic potential of perivascular adipose tissue preadipocytes is improved by coculture with primary adipocytes, in press, Cytotechnology, doi:10.1007/s10616-018-0238-0, 2018. PMID: 30051281, 2018.
Watts, S. W. and Gollasch M: Peirvascular adipose tissue (PVAT) in health and disease. Front Physiology, Vasc Physiology doi.org/10.3389/fphys.2018.01004, 2018. PMID: 30104983, 2018.
2019
Kumar R. K., Darios, E. S., Burnett, R. and Watts, S. W.: Fenfluramine-induced PVAT-dependent contraction of rat aorta depends on norepinephrine and not serotonin, Pharmacol Res, 140:43-49, 2019. PMID: 30189295, 2019.
Ahmad, M., Ayala-Lopez, N., Darios, E; Ismail, A, Ferland, D., Burnett, R., Anantharam, A. and Watts, S. W. Perivascular adipocytes store norepinephrine by vesicular transport, Art.. Thromb. Vasc. Biol., 39:188-199, 2019. PMID: 30567483, 2019.
Watts, S. W., Chatterjee, D., Rojewski, J. W., Reiss, C. S., Baas, T., Gould, K. L., Brown, A. M., Chalkely, R., Brandt, P., Wefes, I., Hyman, L. and Ford, J. K.: Faculty perceptions and knowledge of career development of trainees in biomedical science: what do we (think we) know? PLoS ONE, Jan 30;14(1):e0210189. doi: 10.1371/journal.pone.0210189, 2019. PMID: 3069914, 2019.
Demireva EY, Xie H, Flood ED, Thompson JM, Seitz BM and Watts SW: Creation of the 5-hydroxytryptamine receptor knockout (5-HT7 KO) rat as a tool for cardiovascular research, Physiological Genomics, 51:290-301, 2019. PMID: 31125290, 2019.
Seitz, B. M., Demireva, E. Y., Xie, H., Fink, G. D., Krieger-Burke, T., Burke, W M. and Watts, S.W.: 5-HT does not lower blood pressure in the 5-HT7 knockout rat, Physiological Genomics, 51: 302-310, 2019. PMID: 31125292, 2019.
St Clair, Rebekah, Rojewski JW, Ford JK, Hutto T, McCarty, N. A., Watts, S. W., Chatterjee, D and Melkers, J. Doctoral Trainee Preferences for Career Development Resources: The Influence of Peer and Other Supportive Social Capital. Int. J. Doctoral studies, vol 14, 2019. Not curated on Pumb Med
Phan HTN, Jackson W. F., Shaw, V. S., Watts, S. W. and Neubig, R. R.: Loss of function mutations in human RGS2 differentially regulated pharmacological reactivity of resistance vasculature, accepted, Mol Pharmacol, 96:926-834, 2019. PMID: 31645376, 2019.
Ferland DJ, Flood ED, Garver H, Yeh ST, Riney S, Mullick AE, Fink GD and Watts SW: Different blood pressure responses in hypertensive rats following chemerin mRNA inhibition in dietary high fat compared to dietary high salt conditions, Physiological Genomics, 51:553-561, 2019. PMID: 31588871, 2019.
2020
Watts SW, Flood ED, Garver H, Fink GD and Roccabianca S: A new function for perivascular adipose tissue (PVAT): Assistance of arterial stress relaxation, Scientific Reports, 10(1):1807. doi: 10.1038/s41598-020-58368-x, PMID: 32019956, 2020.
Ferland DJ, Garver H, Contreras A, Fink GD and Watts SW: Chemerin contributes to in vivo adipogenesis in a location-specific manner. PLoS ONE, 5(2):e0229251. doi: 10.1371/journal.pone.0229251. PMID: 32092101, 2020.
Kumar RK, Jin Y, Watts SW, Rockwell CE: naïve, regulatory, activated and memory immune cells co-exist in PVATs that are comparable in density to non-PVAT fats in health. Frontiers in Physiology Vascular Physiology, 11:58. doi: 10.3389/fphys.2020.00058. PMID: 32116768, 2020.
Watts SW, Klomparens K and Rojewski JW: Michigan State University BEST: Lessons Learned, chapter in the “BEST: Implementing career development activities for biomedical research trainees”, ISBN: 9780128207598, Elsevier publishing, 2020. Not curated on PubMed
Ferland DJ, Mullick AE, Watts SW: Chemerin as a driver of hypertension: a consideration. Am. J Hypertension, May 2020. hpaa084. doi: 10.1093/ajh/hpaa084. PMID: 32453820, 2020/
Flood ED and Watts SW: Endogenous chemerin from PVAT amplifies electrical field stimulated arterial contraction: use of the chemerin knockout rat, invited submission for Adipokines 3.0, Int J Mol Sci, Sep 2;21(17):6392, PMID: 32887510, 2020.
Contreras GA, Yang Y, Flood E, Garver H, Bhattacharya S, Fink GD and Watts SW: Blood ressure changes PVAT function and transcriptome: use of the mid-thoracic coarcted rat, Am J Physiol Heart Circ Physiol. 2020 Dec 1;319(6):H1313-H1324. doi: 10.1152/ajpheart.00332.2020. PMID: 33006918, 2020.
Seitz BM, Fink GD and Watts SW: Activation of 5-HT7 receptor but not NOS is necessary for chronic 5-HT-induced hypotension. Experimental Physiol, 2020 Oct 14. doi: 10.1113/EP088919, PMID 33052620, 2020.
2021
Nicholas M. Barnes, Gerard P. Ahern, Carine Becamel, Joël Bockaert, Michael Camilleri, Severine Chaumont-Dubel, Sylvie Claeysen, Kathryn A. Cunningham, Kevin C. Fone, Michael Gershon, Giuseppe Di Giovanni, Nathalie M. Goodfellow, Adam Halberstadt, Rachel M. Hartley, Ghérici Hassaine, Katharine Herrick-Davis, Ruud Hovius, Michael T. Klein, Enza Lacivita, Evelyn K. Lambe, Marcello Leopoldo, Finn Olav Levy, Sarah C.R. Lummis, Philippe Marin, Luc Maroteaux, Andrew C. McCreary, David L. Nelson, John F. Neumaier, Adrian Newman-Tancredi, Hugues Nury, Alexander J. Roberts, Bryan L. Roth, Anne Roumier, Gareth J. Sanger, Milt Teitler1 Trevor Sharp, Carlos M. Villalón, Horst Vogel, Stephanie W. Watts, Daniel Hoyer. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine: Pharmacology and function. Pharmacol Rev. 73(1):310-520. doi: 10.1124/pr.118.015552. PMID: 33370241, 2021.
Grobbel MR, Lee LC, Watts SW, Fink GD, Roccabianca S: Left ventricular geometry, tissue composition, and residual stress in high fat diet dahl salt sensitive rats. Experimental Mechanics, 61:191-201. PMID 33776071, 2021.
Chatterjee D, Rojewski J, Watts SW, Ford JK: Broadening Experiences in Scientific Training (BEST): Do biomedical faculty want institutional Support? SN Soc Sci 1: 27 dpo/prg10.1007/s43545-020-00029-x. 2021. Not curated on PubMed.
Watts, S. W, Alexander, B., Baylis, C., Brown, N., Cassis, L., Denton, K. Joe, B., Lerman, L. Oparil, S., Reckelhoff, J., Sandberg, K. and Touyz, R. M.: Connecting generations of scientists in the Council on Hypertension through Harriet Dustan, Hypertension 77:296-307, PMID: 33390045, 2021.
Kumar, R. K., Kaiser, L. M., Rockwell, C. E. and Watts, S. W.: Interleukin-10 does not contribute to the anti-contractile nature of PVAT in health. Vasc Pharmacol. doi:10.1016/j.vph.2021.106838. PMID: 33540122, 2021.
Kumar, R. K., Yang, Y., Contreras, G. A., Garver, H., Bhattacharya, S., Fink, G. D., Rockwell, C. E. and Watts, S. W.: Phenotypic changes in T cell and macrophage subtypes in perivascular adipose tissues prece high fat diet induced hypertension, Front Physiol. 2021 Mar 17;12:616055. doi: 10.3389/fphys.2021.616055. eCollection 2021. PMID: 33815135, 2021.
Restini, C., Fink, G. D. and Watts, S. W.: Vascular reactivity stimulated by TMA and TMAO: Are perivascular adipose tissue and endothelium involved? Pharmacol Res, 2021 Jan;163:105273 doi: 10.1016/j.phrs.2020.105273. PMID 331975899, 2021.
Orr, A., Thompson, J, Lyttle, J and Watts, S. W.: Transglutaminases Are Active in
Perivascular Adipose Tissue” invited submission for Adipokines 3.0, Int J Mol Sci. 2021 Mar 5;22(5):2649. doi: 10.3390/ijms22052649. PMID: 33808023, 2021.
Rojewski JW, Ayala-Lopez N, Nguyen S and Watts, S. W.: Using data to make the case for program resources and sustainability: the BEST action inventory case study. SN Soc Sci 1:140, doi.org/10.1007/x43545-021-00137-2, 2021. Not curated on PubMed.
Ayala-Lopez N and Watts, S. W.: Physiology and Pharmacology of Neurotransmitter Transporters, Compr Physiol, 11:2279-2285, PMID: 34190339.
Watts, S. W., Darios, E. S., Contreras G. A., Garver, H. and Fink, G. D.: Male and female high fat fed Dahl SS rats are largely protected from vascular dysfunctions: PVAT contributions reveal sex differences. Am J Physiol. Heart Circ Phys, 321:H15-H28. PMID: 33929898.
Gonzalez-Pons, R., McRae, K., Thompson, J. M. and Watts, S. W.: The 5-HT7 receptor restrains 5-HT-induced 5-HT2A mediated contraction in the isolated abdominal vena cava. J Cardiovasc Pharmacol, 78:319-327, PMID: 34029269
Wenceslau C, McCarthy C, Earley S, England S, Filosa J, Goulopoulou S, Gutterman D, Isakson B, Kanagy N, Martinez-Lemus L, Sonkusare S, Thakore P, Trask A, Watts, S.W., and Webb RC: Guidelines for the measurement of vascular function and structure in isolated arteries and veins" Am J Physiol Heart Circ Physiol, 321:H77-H111. PMID: 33989082.
Seitz, B. M., Fink, G. D. and Watts, S. W.: Reduction in hindquarter vascular resistanced supports 5-HT7 receptor mediated hypotension, Front Physiology Integr Physiol, 2021 Jun 24;12:679809. doi: 10.3389/fphys.2021.679809. eCollection 2021. PMID: 34248666.
2022
Miron TR, Flood ED, Tykocki NR, Thompson JM, Watts SW: Identification of Piezo1 channels in perivascular adipose tissue (PVAT) and potential role in vascular function. Pharmacol Res 175:105995. doi: 10.1016/j.phrs.2021.105995. Epub 2021 Nov 21. PMID: 34818570.
Tuttle T, Darios EM, Watts SW and Roccabianca S: Arterial stiffness is lower when perivascular adipose tissue (PVAT) is included, Am J. Physiol Heart Circ, 2022. Mar 11. doi: 10.1152/ajpheart.00574.2021. 2022
Watts SW, Darios E, Thompson: Is the 5-HT7 receptor constitutive active in the vasculature? A study in Veins/vain, J Cardiovasc Pharmacol, 80:314-322, 2022.
•Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Reply to Boedtkjer and Aalkjaer. Am J Physiol Heart Circ Physiol. 2022 Apr 1;322(4):H687-H688. doi: 10.1152/ajpheart.00117.2022. PMID: 35324334 Free PMC article. No abstract available.
Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Reply to De Mey et al. Am J Physiol Heart Circ Physiol. 2022 Apr 1;322(4):H683-H684. doi: 10.1152/ajpheart.00086.2022. PMID: 35324332 Free PMC article.
•(Invited Chemerin issue) Orr A, Liu K, Mullick A, Huang X, Watts, S. W.: Divergence of chemerin reduction abilities of ATS9R nanoparticle targeting adipose tissue in vitro vs in vivo in the rat, Biomedicines, 10(7):1635. Doi:3390/biomedicines10071635, 2022.
Contreras GA, Rendon CJ, Flood E, Thompson JM, Chirivi M and Watts SW: PIEZO1 mechanoreceptor activation reduces adipogenesis in perivascular adipose tissue preadipocytes, Frontiers in Endocrin, 2022 Aug 31;13:995499. doi: 10.3389/fendo.2022.995499. eCollection 2022. PMID: 36120469.
Watts SW, Mullick AE, Garver H, Orr A and Fink GD: A high fat diet does not stimulated blood pressure dependence on chemerin in the Sprague-Dawley Rat, in press, American Heart Journal Plus, https://doi.org/10.1016/j.ahjo.2022.100205
Trask A, Bellow N, Carnevale D, Arnold A and Watts SW: Hypertension Section Editors Series: early career introduction and update, accepted, Hypertension, Dec 2022.
2023
•Trask A, Bellow N, Carnevale D, Arnold A and Watts SW: Hypertension Section Editors Series: early career introduction and update, Hypertension, 80:493-496, 2023.
•Butler B, Garver H, Watts SW and Fink GD: Skin vascular resistance decreases during 5-HT-induced hypotension in the rat, Biomedicines, Feb 13;11(2):547. doi: 10.3390/biomedicines11020547, 2023.
•Thompson JM, Tragge W, Flood ED, Schulz S, Lisabeth E and Watts SW: Development of a validated 5-HT7 receptor antibody for the rat, Naunyn-Schmiedebergs Arch Pharmacol doi: 10.1007/s00210-023-02482-w. Online ahead of print.
•Jackson WF, Daci A, Thompson JM, Fink GD and Watts SW: 5-HT7 receptors mediate dilation of rat cremaster muscle arterioles in vivo, Microcirculation, e12808.
doi: 10.1111/micc.12808, 2023.
•Wabel E, Orr A, Flood E, Thomspon J, Xie H, Demireva E, Abolibdeh B, Honke-Hulbert D, Mullick A, Garver H, Fink G, Kung T and Watts SW : Chemerin is resident to vascular tunicas and contributes to vascular tone, Am J Physiol Heart Circ Physiology, May 2023.
2024
•Wilson C, Thompson JM, Terrian L, Lauver AD, Flood ED, Fink GD, Sather L, Bhattacharya S, Contreras A and Watts SW: What a difference hypertension makes: the adventitia hands off to PVAT for extracellular matrix remodeling as blood pressure rises in the high fat fed Dahl SS rat, J Vasc Res, doi: Dec 19:1-12. doi: 10.1159/000535513, 2024
•Watts, S. W., Garver, H., Morisset-Lopez, S., Suzenet, F., and Fink, G. D.: Beta-arrestin biased signaling is not involved in the hypotensive actions of 5-HT7 receptor stimulation: use of Serodolin, Pharmacological Research, 199:107047. doi: 10.1016/j.phrs.2023.107047, 2024
•Watts SW, Townsend, R. R and Neubig, R. R. How developments in pharmacology receptor theory are changing (our understanding of) hypertension therapy, invited Review, Am J Hypertension, 37:248-260, 2024.
•Thompson, J. M., Watts, S. W., Terrian, L., Contreras G. A., Rockwell, C., Rendon, C. J., Wabel, E., Lockwood, L., Bhattacharya, S. and Nault, R. : A cell atlas of thoracic aortic perivascular adipose tissue: a focus on mechanotransducers, AJP Heart and Circ Phys, doi: 10.1152/ajpheart.00040.2024, 2024.
•Jin Y, Liu S, Guzman KE, Kumar RK, Kaiser LM, Garver H, Bernard JJ, Bhattacharya S, Fink GD, Watts SW and Rockwell CE: Secretion of pro-inflammatory cytokines by activated T cells culture in PVAT-conditioned media from Dahl S rats on a high fat diet occurs early during development of hypertension, in press, April Plos ONe
•Ewart SL, Mavess BE, Latona O, Young L, Sawtelle V, Watts SW and Yuzbasiyan-Gurkan V. BRUSH Summer Research Program: promoting underrepresented student science identity in biomedical Science. J Vet Med Educ, in press, April 2024. .
•Hanscom, M., Morales-Soto, W., Watts, S. W., Jackson, W. F. and Gulbransen, B. D. Lack of evidence for innervation of perivascular adipocytes in mice; in press, AJP Heart and Circ May 2024.